Toothache science: proteins may reveal why some pulpitis hurts more
NCT ID NCT06938191
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at certain proteins (aquaporins and IL-8) in the fluid and tissue of healthy teeth and teeth with a painful, inflamed nerve (irreversible pulpitis). Researchers will collect samples from 70 adults during routine root canal treatment to compare protein levels. The goal is to better understand the biology of tooth inflammation, not to test a new treatment.
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