Zirconia vs titanium: which dental implant heals bone better?

NCT ID NCT05890469

Completed Knowledge-focused Sponsor: Queen Mary University of London Source: ClinicalTrials.gov ↗

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study compares how zirconia and titanium dental implants affect early bone healing in people needing a single tooth replacement. Researchers will measure healing biomarkers in gum fluid and saliva over 30 days, and track blood flow and tissue changes. The goal is to understand which implant surface material and texture may support better bone regeneration.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: zirconia dental implant with guided bone regeneration
What this could lead to: If successful, this study could help dentists choose better implant materials for faster and more predictable bone healing.
What could go wrong: This is a very small pilot study with only 12 participants, so results may not apply to everyone. It looks at early healing markers, not long-term implant success.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BIOMARKERS DENTAL IMPLANT GUIDED BONE REGENERATION SALIVA

Contacts and locations

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Locations

Barts Health NHS Trust Dental Hospital

London, E1 1BB, United Kingdom
Centre for Oral Clinical Research

London, E1 2AD, United Kingdom

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