Simple test could slash use of Last-Resort antibiotics for UTIs
NCT ID NCT07675018
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This trial investigates whether a rapid test for antibiotic resistance genes (integrons) can help doctors choose narrower-spectrum antibiotics for hospitalized adults with urinary tract infections (UTIs). Participants must have had a recent infection with a resistant bacterium. Those whose test is negative will receive a standard third-generation cephalosporin instead of stronger drugs like carbapenems. The goal is to see if this approach reduces the number of days patients are treated with broad-spectrum antibiotics without compromising recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Detection of integrons (diagnostic test)
What this could lead to
If successful, this test could help doctors avoid using strong, broad-spectrum antibiotics for many urinary tract infections, reducing the risk of antibiotic resistance.
What could go wrong
This is a relatively small, early-stage trial. The test may not accurately predict resistance in all cases, and the approach may not work for all patients or settings.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHRU Tours, Hôpital Trousseau
Chambray-lès-Tours, 37170, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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CHU de Reims
Reims, 51100, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Grenoble university hospital
La Tronche, 38700, France
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Groupe Hospitalier Universitaire Bichat-Claude Bernard - APHP
Paris, 75018, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Hopital lariboisière
Paris, 75010, France
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Hôpital Saint Louis - APHP
Paris, 75010, France
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Limoges university hospital
Limoges, 87042, France