University Hospital, Limoges

This study tests whether giving immunosuppressive drugs as a single daily dose after liver transplant works as well as the standard twice-daily regimen. About 162 adult liver transplant recipients will be randomly assigned to once-daily or twice-daily dosing. The goal is to see i…

This study looks at whether nurses measuring blood flow in tiny vessels (microcirculation) can help treat sepsis patients earlier in the emergency room. Sepsis is a serious infection that can quickly get worse, even when standard vital signs look normal. The study will include 55…

This study tests if a drug called Interferon gamma can prevent new infections in intensive care unit (ICU) patients whose immune systems are weakened. About 326 adults who have been in the ICU for at least a week will receive either the drug or a placebo. The goal is to see if th…

This study tests a special home-based program (COTID) for people aged 75+ with dementia who were hospitalized after a fall. The program involves an occupational therapist making home safety changes and training a family caregiver to provide support. Researchers will track whether…

This study compares two drugs used during gallbladder surgery to see which one helps patients recover better with fewer side effects. One drug, sufentanil, is a common morphine-like painkiller that can cause nausea, confusion, and itching. The other, esmolol, is a heart medicatio…

This study looks at a kidney disease called IgA nephropathy, which can lead to kidney failure. Researchers want to find special markers in the blood that could help diagnose the disease without needing a kidney biopsy. They will study 150 adults who need a kidney biopsy as part o…

This study looks at how filtering affects the key ingredients in eye drops made from a patient's own blood (autologous serum) for severe dry eye disease. Ten adults with dry eye that hasn't improved with standard treatments will provide blood samples. Researchers will measure lev…

This study is creating a large group of children with idiopathic nephrotic syndrome, a rare kidney disease. Researchers will collect information on their health, treatments, and side effects over time. The goal is to better understand the disease and make it easier to run future …

This study is collecting information from French medical centers that specialize in a precise colon procedure called endoscopic submucosal dissection (ESD). The goal is to see how well it removes large colon growths and to track any complications or recurrences. About 1,200 peopl…

This study looks at genetic changes in natural killer (NK) and B cells—key immune cells—in people with chronic hepatitis B. Researchers want to understand why the immune system fails to clear the virus. About 140 adults with or without hepatitis B will provide blood samples for g…