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Heart drug could replace morphine in gallbladder surgery recovery

NCT ID NCT07019818

Recruiting now Symptom relief Sponsor: University Hospital, Limoges Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a heart medication called esmolol can replace the morphine-like drug sufentanil during gallbladder surgery to improve recovery. About 120 adults having outpatient gallbladder surgery will receive either esmolol or sufentanil. The goal is to see if esmolol provides similar pain control and comfort with fewer side effects like nausea and vomiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Esmolol (a heart-specific beta-blocker) and Sufentanil (a morphine-like painkiller)
What this could lead to
If esmolol works as well as sufentanil, it could offer a way to manage pain during surgery without morphine-related side effects like nausea and vomiting.
What could go wrong
This is a small, early-phase study with only 120 participants. Esmolol may not control pain as effectively, and it can cause low blood pressure or breathing problems.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LAPAROSCOPIC CHOLECYSTECTOMY SURGERY

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CH Brive

    RECRUITING

    Brive-la-Gaillarde, France, 19100, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CHU Limoges

    RECRUITING

    Limoges, France, 87042, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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