Could a simple blood test unlock ALS weight loss mystery?

NCT ID NCT06147843

Recruiting now Knowledge-focused Sponsor: University Hospital, Limoges Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 2 times

Summary

This study is looking for biological clues in the blood that explain why many people with ALS lose weight. Researchers will follow 1,000 patients in France and Germany, collecting blood samples and questionnaires alongside standard care. The goal is to find markers that could lead to new treatments to prevent weight loss and improve survival.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could identify the causes of weight loss in ALS, pointing toward new treatments to improve survival and quality of life.
What could go wrong: This is an observational study, not a treatment trial. It may not directly lead to a therapy, and results may take years to translate into clinical practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

amyotrophic lateral sclerosis Inflammation Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AMYOTROPHIC LATERAL SCLEROSIS

Contacts and locations

Locations

CHU de Lille
RECRUITING

Lille, 59037, France
CHU de Nice
RECRUITING

Nice, 06001, France
CHU de Tours
RECRUITING

Tours, 37044, France
Hôpital Gui Chauliac
RECRUITING

Montpellier, 34295, France
Hôpital de la Pitié Salpêtrière
RECRUITING

Paris, 75013, France
Hôpital de la Timone
RECRUITING

Marseille, 13005, France
Klinik für Medizinische Hochschule Hannover Carl-Neuberg-Str. 1
NOT_YET_RECRUITING

Hanover, Allemagne, 30625, Germany
Klinik für Neurologie, Universitäts- und Rehabilitationskliniken Ulm (RKU
NOT_YET_RECRUITING

Ulm, Allemagne, 89081, Germany
Limoges University Hospital
RECRUITING

Limoges, 87042, France

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