Could a simple blood test unlock ALS weight loss mystery?
NCT ID NCT06147843
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is looking for biological clues in the blood that explain why many people with ALS lose weight. Researchers will follow 1,000 patients in France and Germany, collecting blood samples and questionnaires alongside standard care. The goal is to find markers that could lead to new treatments to prevent weight loss and improve survival.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could identify the causes of weight loss in ALS, pointing toward new treatments to improve survival and quality of life.
What could go wrong
This is an observational study, not a treatment trial. It may not directly lead to a therapy, and results may take years to translate into clinical practice.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHU de Lille
NOT_YET_RECRUITINGLille, 59037, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU de Nice
NOT_YET_RECRUITINGNice, 06001, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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CHU de Tours
NOT_YET_RECRUITINGTours, 37044, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital Gui Chauliac
NOT_YET_RECRUITINGMontpellier, 34295, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital de la Pitié Salpêtrière
NOT_YET_RECRUITINGParis, 75013, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hôpital de la Timone
NOT_YET_RECRUITINGMarseille, 13005, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Limoges University Hospital
RECRUITINGLimoges, 87042, France
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••