A muscle test in the thigh may reveal how ALS attacks the body

NCT ID NCT06284161

Recruiting now Knowledge-focused Sponsor: University Hospital, Clermont-Ferrand Source: ClinicalTrials.gov ↗

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This study tests whether a non-invasive electrical test on the quadriceps (thigh muscle) can help diagnose and monitor amyotrophic lateral sclerosis (ALS). Researchers will measure nerve signals traveling from the brain to the muscle in 30 people with suspected or confirmed ALS. The goal is to see if this test can detect early damage to the motor pathway and track how the disease changes over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Quadriceps Combined Test (motor-evoked potentials)
What this could lead to: If successful, this test could provide a new way to diagnose ALS earlier and track its progression more objectively.
What could go wrong: This is a small, early-stage study with only 30 participants. The test may not prove useful for all ALS patients or may not correlate well with disease progression.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AMYOTROPHIC LATERAL SCLEROSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

amyotrophic lateral sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AMYOTROPHIC LATERAL SCLEROSIS

Contacts and locations

Locations

CHU de Clermont-Ferrand
RECRUITING

Clermont-Ferrand, 63000, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.