University Hospital, Limoges

This study looked at kidney and liver transplant patients to see if switching from a twice-daily tacrolimus (Prograf) to a once-daily version (Envarsus) keeps the drug at safe and effective levels in the blood. About 134 adults who had a transplant within the past year took part.…

This study looked at 156 people with advanced non-small cell lung cancer that had come back after initial treatment. It compared a combination of two drugs (erlotinib and docetaxel) given in sequence versus docetaxel alone. The goal was to see if the combination could help keep t…

This study tested whether home automation sensors and remote monitoring by doctors could help elderly people (65+) with multiple chronic diseases live safely at home and avoid unplanned hospital stays. Over 500 participants had their homes equipped with sensors to track health si…

This study compares two procedures for removing large, flat colon polyps: endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR). The goal is to see which method leads to fewer polyps coming back and which is more cost-effective over time. About 360 adults …

This study tested whether a drug called dobutamine could help people with septic shock who also have heart muscle weakness. The trial included 136 adults in intensive care. Researchers measured how organ function changed over three days to see if the drug improved blood flow and …

This study tested whether a lab technique called flow cytometry can accurately diagnose allergies to muscle relaxant drugs used during anesthesia. Researchers studied 129 adults who had a suspected allergic reaction during a previous surgery. The goal was to identify which drug c…

This study tested whether chewing gum can help diagnose giant cell arteritis (Horton's disease), a condition where blood vessels become inflamed. Researchers asked 66 people to chew gum and checked if it caused jaw pain, which is a common symptom. The goal was to see if this simp…

This study looked at whether adding a relaxing touch technique to standard pain medicine can lower pain when removing a Redon drain in children aged 7 to 17 after surgery. About 232 children took part. The goal was to see if this drug-free method helps kids feel less pain during …

This study tested a program where parents and children prepare together before surgery to see if it lowers children's anxiety. Fifty children aged 5 to 12 having scheduled surgery took part. The program aimed to help parents be present and supportive during anesthesia induction. …

This pilot study looked at two different pain management techniques in 40 patients aged 70 and older who had a hip fracture and were waiting for surgery. The goal was to see which method better controlled pain and helped prevent pressure ulcers during the wait. The study focused …

This study tested whether adding a specific massage technique (manual lymphatic drainage) to standard physical therapy helps people regain knee movement faster after knee replacement surgery. The study involved 44 adults who had knee replacement and compared those who received th…

This completed study looked at how leg muscles activate during walking in 500 people who had a stroke. Researchers aimed to improve understanding of muscle patterns and find early signs that predict walking recovery. The goal is to use these insights to create better, personalize…

This study looked at how often people with primary Sjögren's syndrome have digestive issues. Researchers used a questionnaire to track 10 different digestive symptoms in 151 adults. The goal was to better understand these hidden symptoms and how they relate to the disease.

This study checked 878 people in Limousin, France for signs of tick-borne encephalitis virus (TBEV). Researchers looked for antibodies in blood samples from patients who had Lyme disease tests or brain inflammation symptoms. The goal was to find out if TBEV is present in the area…

This study surveyed 121 adults with autoimmune diseases like lupus or Sjögren's syndrome to find out how many use alternative medicines (such as herbal remedies or acupuncture). Participants filled out an anonymous questionnaire. The goal was simply to count and describe these pr…

This study looked at how the heart's pumping and filling ability affects survival in people with septic shock, a severe infection that causes organ failure. Researchers studied 440 ICU patients to see if heart problems lead to fluid overload and higher death risk. The main goal w…

This study looked at how the antifungal drug micafungin behaves in 60 critically ill ICU patients with invasive candidiasis, a serious fungal infection. The goal was to see if standard doses reach effective levels in these patients, since their bodies often process drugs differen…

This study looked at whether using an early heart ultrasound (echocardiography) in the emergency room can help guide treatment for people with sepsis or septic shock. The goal was to see if this approach reduces organ damage compared to standard care. The study involved 312 adult…

This study tested if letting parents watch and help with syringe feeding (instead of using a machine) encourages them to spend more time in the neonatal unit. 72 premature babies born between 30-34 weeks took part. The goal was to see if this simple change increases parental pres…

This study looked at how doing a thinking task while walking affects the brain activity of stroke survivors. 11 people who had a stroke walked on a special mat while wearing a brain scanner. The goal was to understand why walking can become harder when you have to think at the sa…

This study followed 400 stem cell transplant recipients to see how well newer anti-CMV drugs work in everyday practice and whether the virus becomes resistant. Researchers tracked infections, drug side effects, and survival. The goal is to improve treatment guidelines for high-ri…

This study looked at how scleroderma, an autoimmune disease, limits hand movement in 30 adults. Researchers measured joint motion and skin tightness in both the dominant and non-dominant hand to see which is more affected. The goal was to better understand hand disability to guid…