University Hospital, Limoges

This pilot study tested whether the multiple myeloma drug carfilzomib can be safely given at home instead of in a hospital. Seventeen patients received their first cycle in the clinic and later cycles at home, with nurses administering the short infusion. The main goal was to see…

This phase 2 study tested whether adding the targeted drug erlotinib to standard chemotherapy (docetaxel) works better than chemotherapy alone for people with advanced non-small cell lung cancer whose first treatment stopped working. 156 participants were randomly assigned to one…

This study compared two procedures for removing large, flat colon polyps (over 25 mm) in 360 adults. One method, ESD, removes the polyp in one piece but has higher risks and costs. The other, EMR, removes it in pieces but is safer and cheaper. The goal was to see which leads to f…

This study looked at 134 kidney or liver transplant patients who switched from taking tacrolimus twice a day (Prograf) to once a day (Envarsus). Researchers measured drug levels in the blood before and after the switch to see if the once-daily version provides similar exposure. T…

This completed Phase 3 trial tested whether dobutamine, a heart-strengthening drug, can reduce organ failure in 136 ICU patients with septic cardiomyopathy and low blood flow. Patients received either dobutamine or a placebo alongside standard care. The study measured changes in …

This study tested a new tool called BESTA, designed to quickly diagnose aphasia (language problems) in people who just had a stroke. Researchers compared BESTA to an existing test in 395 participants, including stroke patients and healthy volunteers. The goal was to see if BESTA …

This study tested whether chewing gum can help doctors diagnose giant cell arteritis (Horton's disease), a condition where blood vessels become inflamed. The idea is that chewing may trigger jaw pain in people with the disease, making it easier to spot. Researchers compared resul…

This study looked at whether a blood test called flow cytometry can accurately diagnose allergic reactions to muscle relaxants given during anesthesia. Researchers tested 129 adults who had a suspected allergic reaction during a past surgery. The goal was to see if the test could…

This study tested whether regular telemedicine visits could prevent emergency room trips and hospital stays for elderly nursing home residents with multiple health problems. Over 400 residents in 9 French nursing homes received a telemedicine check-up every 3 months for a year, p…

This study tested whether a personalized home exercise program (walking three times a week and strength training with elastic bands twice a week) could improve fitness and strength in 30 adults waiting for a liver transplant. The goal was to see if better fitness before surgery c…

This study tested whether listening to music during wound dressing changes can reduce pain in people with severe arteritis (stage 5 or 6). Twenty-five patients were asked to listen to music during their daily wound care. The main goal was to see if pain levels were lower on a 0-1…

This study tested whether practicing Qi Gong, a gentle mind-body exercise, could improve quality of life in people with systemic lupus erythematosus (SLE). Thirty-three participants took part in weekly Qi Gong sessions for six months. Researchers measured changes in physical func…

This study tested whether adding manual lymphatic drainage massage to standard physiotherapy helps people recover knee movement faster after knee replacement surgery. Researchers measured joint range, swelling, and pain in 44 patients during their first week in the hospital. The …

This study tested a program where parents and children prepare together before surgery to see if it lowers children's anxiety when they get anesthesia. Fifty children aged 5 to 12 having planned surgery took part. The program involved parents being present and prepared for the op…

This study looked at whether adding a relaxing touch technique to standard pain medicine could reduce pain when removing a Redon drain in children aged 7 to 17. About 232 kids took part. The goal was to see if this drug-free method could lower pain scores right after the drain wa…

This pilot study tested two ways to manage pain in patients aged 70 and older who had a hip fracture and were waiting for surgery. One method used a continuous pulling technique on the skin, and the other used a pillow placed between the legs. The goal was to see which approach c…

This completed study tested whether brain wave recordings (event-related potentials) can detect cognitive processing in people with brain injuries, including those with altered consciousness. Researchers compared 320 patients and healthy adults using high-density EEG. The goal wa…

This completed pilot study looked at whether nursing home staff in areas with few doctors would accept using artificial intelligence and telemedicine to help care for elderly residents. The study involved 137 participants aged 65 and older living in nursing homes located in medic…

This study looked at whether asking people with multiple sclerosis (MS) to do two things at once — like walking while thinking — can uncover balance problems that standard tests miss. Researchers studied 24 people with mild MS and low disability. The goal was to see if this dual-…

This study looked at the emotional well-being of healthcare workers treating COVID-19 patients at two French hospitals. 78 staff members completed questionnaires about anxiety, depression, resilience, and empathy at different times during the pandemic. The goal was to understand …

This study tested over 1,500 hospital workers in four French hospitals for COVID-19 antibodies to see how many had been infected. Researchers compared infection rates among staff in COVID-19 units, other care areas, and non-care roles, and across regions with different outbreak i…

This study followed 92 people who had mild COVID and were treated at home. Two years after their diagnosis, they answered a questionnaire by mail about any hospital visits or other health events. The goal was to learn how outpatients fare over time and find patterns that could he…

This study looked at 30 people with early-stage non-small cell lung cancer who had surgery. Researchers collected blood from a vein near the tumor and from a regular arm vein to study tiny particles called exosomes. The goal was to see if these particles could help predict whethe…

This study looked at the IgA antibodies in 80 people — 40 with IgA nephropathy (a kidney disease) and 40 healthy volunteers. Researchers took one blood sample from each person to analyze the IgA repertoire. The goal was to understand why IgA deposits form in the kidneys, which co…

This study tested a decision algorithm to help doctors diagnose the cause of eosinophilia (high levels of a type of white blood cell). The algorithm guides which tests to do and in what order. Researchers enrolled 53 patients and measured how many followed the algorithm correctly…

This study looks at what people with age-related macular degeneration (AMD) know about their disease and what they need to manage it better. Researchers will survey and interview 118 patients to understand their knowledge, daily challenges, and support needs. The goal is to use t…

This completed study monitored 1560 adults hospitalized with invasive pneumococcal infections (excluding meningitis) across France. Researchers collected information on infection severity, risk factors, and bacterial serotypes to understand how these infections occur and how vacc…

This study looked at two different ways to feed patients who are on mechanical ventilators. The goal was to see which method causes fewer problems like diarrhea, vomiting, or pneumonia. One hundred adult patients were enrolled, and researchers measured how much nutrition they act…

This study looked at whether a simple saliva test can find cytomegalovirus (CMV) in children aged 3 months to 6 years. Researchers collected saliva samples from 655 children in daycares and a hospital emergency department. The goal was to see how common the virus is and to check …

This study involved 10 adults with severe dry eye disease who did not respond to standard treatments. Researchers measured levels of growth factors and vitamins in autologous serum eye drops before and after filtration, to see if filtering reduces their concentration. The goal is…

This completed study tested blood samples from 878 people in Limousin, France, for antibodies against tick-borne encephalitis virus (TBEV). The goal was to see if the virus is present in the region, especially in patients with Lyme disease or neurological symptoms. Researchers al…

This study looked at how often people with primary Sjögren's syndrome have digestive issues. Researchers asked 151 patients about 10 different digestive symptoms using a simple questionnaire. The goal was to understand which symptoms are most common and how they relate to how lon…

This completed study looked at how leg muscles work during walking in 500 people who had a stroke. The goal was to understand muscle patterns, test how well current measurement methods work, and find early signs that predict walking recovery. The results could help doctors create…

This study looked at how doing a thinking task while walking affects the brain in people who have had a stroke. Eleven stroke survivors walked on a special mat while a brain scanner measured their brain activity. The goal was to understand why walking gets harder when you have to…

This study looked at 30 adults with scleroderma, an autoimmune disease that often causes hand stiffness and disability. Researchers measured how much movement was limited in each hand to compare the dominant and non-dominant sides. The goal was to better understand hand function …

This completed study surveyed 121 adults with autoimmune diseases like lupus, Sjögren's syndrome, or scleroderma. Participants filled out a questionnaire about their use of alternative medicines. The goal was to find out how common these practices are in this patient group.

This study tested whether home automation and remote monitoring can help elderly people (65+) with multiple chronic conditions live safely at home. Over 500 participants had their homes equipped with sensors that tracked health signs and sent alerts to doctors. The main goal was …

This study looked at 440 ICU patients with septic shock to see how their heart's pumping and relaxation abilities affected survival. Researchers measured heart function using ultrasound and tracked fluid balance. The goal was to better understand which heart problems are linked t…

This study followed 400 stem cell transplant recipients to see how well anti-CMV medications work in everyday hospital care. Researchers tracked infections, drug resistance, and side effects. The goal was to gather real-life data to improve treatment guidelines for these high-ris…

This study looked at whether doing an early heart ultrasound (echocardiography) in the emergency department helps doctors manage sepsis or septic shock better. 312 adults with sepsis were randomly assigned to either get the ultrasound plus a treatment guide, or standard care. The…

This study looked at how the antifungal drug micafungin is processed in the bodies of 60 critically ill ICU patients with invasive candidiasis. Researchers took multiple blood samples to measure drug levels and understand why some patients might not get enough medicine. The goal …

This study looked at whether allowing parents to push a syringe for their premature baby's tube feeding (instead of using a machine) helps them spend more time in the neonatal intensive care unit. 72 babies born between 30 and 34 weeks were included. The main goal was to compare …