Can a heart drug save sepsis patients? new trial investigates

NCT ID NCT04166331

First seen Nov 21, 2025 · Last updated May 10, 2026 · Updated 22 times

Summary

This study tested whether a drug called dobutamine could help people with septic shock who also have heart muscle weakness. The trial included 136 adults in intensive care. Researchers measured how organ function changed over three days to see if the drug improved blood flow and reduced damage.

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Contacts and locations

Locations

  • Angouleme Hospital

    Angoulême, 16959, France

  • Aphp - Ambroise Paré

    Paris, 75010, France

  • Aphp - Henri Mondor

    Créteil, 94010, France

  • Argenteuil Hospital

    Argenteuil, 95107, France

  • CH d'Haguenau

    Haguenau, 67500, France

  • CH de Bethune

    Béthune, France

  • CH de Brive

    Brive-la-Gaillarde, 19100, France

  • CH de Cannes

    Cannes, France

  • CH de Toulon

    Toulon, 83000, France

  • CHU Orléans - service de Réanimation

    Orléans, Orleans, 47067, France

  • CHU Strasbourg - service de Réanimation

    Strasbourg, Strasbourg, 67000, France

  • CHU Tours - Service de Réanimation

    Tours, Tours, 37044, France

  • Dijon university hospital

    Dijon, 21033, France

  • HCL

    Lyon, France

  • Le Mans Hospital

    Le Mans, 72000, France

  • Lille University Hospital

    Lille, 59045, France

  • Limoges University Hospital

    Limoges, 87042, France

  • Montpellier University Hospital

    Montpellier, 34295, France

  • Nice University Hospital

    Nice, 06202, France

  • Poitiers University Hospital

    Poitiers, 86000, France

  • University Hospital

    Brest, 29200, France

Conditions

Explore the condition pages connected to this study.