New study aims to predict severe kidney injury before it happens

NCT ID NCT05988658

Recruiting now Knowledge-focused Sponsor: University of Chicago Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study is testing whether adding blood and urine biomarkers to a computer risk score can better predict which hospitalized patients will develop severe acute kidney injury (AKI). Researchers will enroll 800 adults at high risk (top 10% by the risk score) and track them for three days. The goal is to improve early detection, not to test a treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a more accurate way to predict severe kidney injury in hospitalized patients, allowing earlier intervention.
What could go wrong: This is an observational study, not a treatment trial. The risk score and biomarkers are being tested for prediction only, and may not improve patient outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute kidney injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE KIDNEY INJURY BIOMARKERS

Contacts and locations

Locations

University of Chicago Medical Center
RECRUITING

Chicago, Illinois, 60637, United States
University of Wisconsin Hospital
RECRUITING

Madison, Wisconsin, 53792, United States

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