Can a short tobacco break curb cannabis cravings?
NCT ID NCT03766971
First seen Sep 01, 2026 · Last updated Sep 02, 2026 · Updated 1 time
Summary
This trial tests whether quitting tobacco for 7 days or 21 days changes how much cannabis people choose to smoke. Adults aged 18 to 60 who use both cannabis and tobacco will be randomly assigned to one of two tobacco cessation periods. Researchers will then measure how many cannabis cigarettes participants choose to smoke, to see if the length of tobacco abstinence affects cannabis relapse.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Tobacco cessation (behavioral) and cannabis (drug)
- What this could lead to
- If quitting tobacco for a short period reduces cannabis relapse, it could point to a simple, practical way to help dual users cut back on cannabis.
- What could go wrong
- This is an early-stage lab study with a small number of participants, so results may not apply to everyone. Quitting tobacco can cause withdrawal symptoms, and the effect on cannabis use may not last.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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About 160 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2020
- Expected to finish
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Nov 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Males and non-pregnant females aged 18-60 years old * Use cannabis * Smoke tobacco cigarettes * Medically and psychologically healthy Exclusion Criteria: * Regular drug use other than cannabis * Current pregnancy/lactation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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New York State Psychiatric Institute
New York, New York, 10032, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- A new weapon against secondhand smoke: home visits that inspire change
- Text messages and clinic prompts may boost smoking cessation
- Mindfulness meets wearable tech in a new bid to break the smoking habit
- Texting teens to tame risky drinking and weed use?
- Can a blood pressure medication curb cannabis cravings?