Scientists test THC and Beta-Myrcene vapor in small human study

NCT ID NCT05432284

Not yet recruiting Knowledge-focused Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This early-stage study will give 32 healthy adults who use cannabis vaporized THC, beta-myrcene, or a placebo to see how these substances affect their feelings of being high and sleepy. Researchers want to learn how beta-myrcene, a compound found in cannabis and other plants, changes the body's response to THC. The study is not yet recruiting and is run by Johns Hopkins University.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: THC (cannabis) and beta-myrcene vapor
What this could lead to: If successful, this could help understand how beta-myrcene changes the effects of THC, potentially leading to better-informed cannabis use.
What could go wrong: This is a very early Phase 1 study with only 32 participants, so results may not apply broadly. It measures subjective effects, not real-world outcomes.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANNABIS USE

Contacts and locations

Locations

Johns Hopkins School of Medicine Behavioral Pharmacology Research Unit

Baltimore, Maryland, 21224, United States

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