Can cannabis curb opioid cravings? new study aims to find out

NCT ID NCT07668635

Not yet recruiting Knowledge-focused Sponsor: Shanna Babalonis, PhD Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study will test whether cannabis can reduce the desire to take opioids in people with opioid use disorder. Thirty participants will live in a hospital for six weeks and receive either cannabis or a placebo, along with opioids. Researchers will measure how many times participants choose to take opioids when given the option.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cannabis
What this could lead to: If it works, this could point toward a way to use cannabis to help people with opioid use disorder reduce their opioid use.
What could go wrong: This is a very early Phase 1 study with only 30 people. It is designed to measure behavior, not to treat the disorder, so results may not lead to a new treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cannabis dependence opiate dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANNABIS USE OPIOID-USE DISORDER

Contacts and locations

Locations

University of Kentucky Center on Drug and Alcohol Research

Lexington, Kentucky, 40508, United States

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Other studies related to the condition(s) this trial covers.