THC brain study aims to uncover why people react differently to cannabis
NCT ID NCT06758596
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-phase study will give 144 healthy young adults (ages 18-21) a single dose of THC (7.5 mg) or a placebo in a capsule, then use brain scans and behavioral tasks to measure how THC affects mood, reward processing, and learning. The goal is to understand why some people respond differently to cannabis, which could inform future research on substance use disorders.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
THC (tetrahydrocannabinol) in a 7.5 mg oral capsule
What this could lead to
If successful, this study could help explain why some people react differently to cannabis, potentially guiding future personalized treatments for substance use disorders.
What could go wrong
This is a very early, small study (144 participants) focused on healthy young adults, so results may not apply to the general population. It is designed to gather knowledge, not to test a treatment.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Illinois at Chicago
Chicago, Illinois, 60612, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••