Can a Stop-Smoking drug also curb cannabis? new trial aims to find out

NCT ID NCT06883162

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether varenicline (Chantix), a drug already used to help people quit smoking, can also help them reduce cannabis use. Two hundred adults in South Carolina who smoke cigarettes and use cannabis will receive either varenicline or a placebo, plus counseling. The goal is to see if the drug helps them quit cigarettes and cut back on cannabis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

varenicline (Chantix)

What this could lead to

If it works, this could offer a new treatment option for people who want to quit smoking and cut back on cannabis at the same time.

What could go wrong

This is a Phase 3 trial, but varenicline is not yet approved for cannabis reduction. Results may not apply to everyone, and side effects like nausea or sleep issues are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cannabis dependence Marijuana Use nicotine dependence Tobacco Use Cessation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Medical University of South Carolina - Charleston

    RECRUITING

    Charleston, South Carolina, 29403, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••