Can a Stop-Smoking drug also curb cannabis? new trial aims to find out

NCT ID NCT06883162

Recruiting now Disease control Sponsor: Medical University of South Carolina Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether varenicline (Chantix), a drug already used to help people quit smoking, can also help them reduce cannabis use. Two hundred adults in South Carolina who smoke cigarettes and use cannabis will receive either varenicline or a placebo, plus counseling. The goal is to see if the drug helps them quit cigarettes and cut back on cannabis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: varenicline (Chantix)
What this could lead to: If it works, this could offer a new treatment option for people who want to quit smoking and cut back on cannabis at the same time.
What could go wrong: This is a Phase 3 trial, but varenicline is not yet approved for cannabis reduction. Results may not apply to everyone, and side effects like nausea or sleep issues are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CANNABIS USE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

cannabis dependence Marijuana Use nicotine dependence Tobacco Use Cessation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANNABIS USE CANNABIS USE DISORDER MARIJUANA USE TOBACCO USE CESSATION TOBACCO USE DISORDER

Contacts and locations

Locations

Medical University of South Carolina - Charleston
RECRUITING

Charleston, South Carolina, 29403, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.