Spit test could replace urine checks for cannabis in remote trials

NCT ID NCT06891235

Recruiting now Knowledge-focused Sponsor: Boston Children's Hospital Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 02, 2026 · Updated 3 times

Summary

This study is testing whether simple saliva tests done at home can accurately show when someone has not used cannabis. Researchers will enroll 200 people aged 18-30 who use cannabis at least once a week. Participants will provide saliva and urine samples over 3-4 weeks, and researchers will compare the test results with self-reported cannabis use. If the saliva tests work well, they could make it easier to run clinical trials remotely without needing in-person urine tests.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: oral fluid test for THC
What this could lead to: If successful, this could provide a reliable, remote way to confirm cannabis non-use in clinical trials, reducing the need for in-person visits.
What could go wrong: This is an early-stage feasibility study with only 200 participants. The tests may not be accurate enough or easy to use at home, and results may not apply to all cannabis users.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cannabis dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANNABIS INTOXICATION CANNABIS USE CANNABIS USE DISORDER

Contacts and locations

Locations

Boston Children's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States

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