Diabetes drug shows promise for quitting smoking without weight gain

NCT ID NCT05610800

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether exenatide, a drug used for diabetes, can help people quit smoking and prevent the weight gain that often happens after quitting. 140 adults who smoked at least 5 cigarettes daily and wanted to quit took part. They received either exenatide or a placebo along with a nicotine patch. The main goals were to see if exenatide improved quit rates and reduced weight gain at 12 weeks.

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Conditions

The condition(s) this trial relates to.

Cigarette Smoking Smoking Smoking Cessation Weight Gain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Michael E. DeBakey VA Medical Center

    Houston, Texas, 77030, United States

  • The University of Texas Health Science Center at Houston

    Houston, Texas, 77054, United States

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