Video games and medication join forces to help people with mental illness quit smoking

NCT ID NCT03950427

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study tests a smoking cessation program designed for adults with serious mental illness. Participants receive a combination of videogame-based physical activity, smoking cessation counseling, and the medication bupropion. The goal is to see if this approach is feasible and acceptable, and whether it helps reduce or stop smoking.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
bupropion, videogame-based physical activity, and counseling
What this could lead to
If successful, this program could offer an effective, engaging way to help people with serious mental illness quit smoking, improving their physical health.
What could go wrong
This is a small, early feasibility study, so results may not apply broadly. The combination approach may not work better than standard methods, and bupropion has side effects.

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Conditions

The condition(s) this trial relates to.

nicotine dependence psychiatric disorder Smoking Cessation Tobacco Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California, San Francisco

    San Francisco, California, 94143-0610, United States

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