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New pill helps smokers kick the habit in major trial

NCT ID NCT04576949

Completed Disease control Sponsor: Achieve Life Sciences Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a pill called cytisinicline to help adults stop smoking. Over 800 daily smokers took the pill or a placebo for 6 or 12 weeks. The goal was to see if the pill helped them stay smoke-free, verified by breath tests. Results showed it was effective for quitting smoking.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Smoking Cessation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SMOKING CESSATION

Contacts and locations

Locations

  • AMR Lexington

    Lexington, Kentucky, 40509, United States

  • Alliance for Multispecialty Research, LLC

    Coral Gables, Florida, 33134, United States

  • Alliance for Multispecialty Research, LLC

    Wichita, Kansas, 67207, United States

  • Alliance for Multispecialty Research, LLC

    New Orleans, Louisiana, 70119, United States

  • Alliance for Multispecialty Research, LLC

    Kansas City, Missouri, 64114, United States

  • Alliance for Multispecialty Research, LLC

    Las Vegas, Nevada, 89119, United States

  • Alliance for Multispecialty Research, LLC

    Norfolk, Virginia, 23502, United States

  • Alliance for Multispecialty Research, LLC.

    Mobile, Alabama, 36608, United States

  • Alliance for Multispecialty Research, LLC.

    Knoxville, Tennessee, 37920, United States

  • Arizona State University

    Phoenix, Arizona, 85044, United States

  • Clinical Research Atlanta

    Atlanta, Georgia, 30281, United States

  • Coastal Carolina Research Center, Inc.

    Mt. Pleasant, South Carolina, 29464, United States

  • FutureSearch Trials of Dallas, LP

    Dallas, Texas, 75231, United States

  • M3 Wake Research, Inc.

    Raleigh, North Carolina, 27612, United States

  • Massachusetts General Hospital - Clinical Genetic Research Facility

    Boston, Massachusetts, 02114, United States

  • MediSphere Medical Research Center, LLC

    Evansville, Indiana, 47714, United States

  • Rochester Clinical Research, Inc.

    Rochester, New York, 14609, United States

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