New study tests if menstrual cycle timing boosts Quit-Smoking success
NCT ID NCT05515354
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study tests whether starting nicotine replacement therapy (patches, gum, or lozenges) at a specific time in the menstrual cycle helps women quit smoking. About 1,200 women who smoke daily and have regular periods will be assigned to start their quit attempt during the follicular phase, luteal phase, or at their usual time. The goal is to see if cycle-timed quitting leads to higher abstinence rates.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- Nicotine replacement therapy (patch, gum, lozenge)
- What this could lead to
- If successful, this could show that timing quit attempts to the menstrual cycle improves smoking cessation rates in women.
- What could go wrong
- This is a large Phase 4 trial, but the effect may be small or not generalizable to all women. Success depends on adherence and individual cycle variability.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Centre for Addiction and Mental Health, Nicotine Dependence Clinic
RECRUITINGToronto, Ontario, M6J 1H4, Canada
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