NICOTINE USE DISORDER

This study looks at whether starting a quit attempt during the first half of the menstrual cycle (follicular phase) helps women stop smoking more successfully than starting during the second half (luteal phase) or without cycle timing. About 1,200 women who smoke daily and have r…

This study tests a gentle, non-invasive brain stimulation technique called temporal interference (TI) to see if it can reduce nicotine cravings and vaping. 120 adults who vape heavily will receive either real stimulation to a deep brain area or a sham (fake) treatment during a si…

This study tests whether a social media and mobile app program can help teens and young adults stop vaping. About 189 participants who vape and want to quit will use a smartphone app with a chatbot that gives personalized tips and support. The goal is to see if the app helps them…

This study works with community leaders and adults who smoke to find out what makes quitting harder and to design a better support program. Researchers will test a new smoking cessation treatment in a small group of 24 people to see if it is practical and well-liked. The goal is …

This study aims to find the best location on the brain to apply magnetic stimulation (TMS) to boost reward signals in smokers. Researchers will test different targeting methods in 36 nicotine-dependent adults across three sessions. The goal is to see which target best increases b…

This study looks at how cooling ingredients like menthol and WS-23 affect how much adults like e-cigarettes and how addictive they might be. About 66 adults who currently vape will try different e-liquid flavors and report their reactions. The goal is to understand if these addit…

This study aims to find the best way to use transcranial magnetic stimulation (TMS) to change how the brain processes rewards in people who are dependent on nicotine. Researchers will test different pulse patterns in 42 smokers to see which one most effectively alters a brain sig…