E-Cig coolants may boost appeal – study investigates
NCT ID NCT05932745
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how cooling ingredients like WS-3 and menthol in e-cigarettes affect how much people like them and find them addictive. Researchers will have 66 adult e-cigarette users try different e-liquid mixtures and report their feelings of liking, craving, and harshness. The goal is to understand which components make e-cigarettes more appealing, which could guide future regulations.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
E-liquid coolants (WS-3, WS-23, menthol)
What this could lead to
If successful, this study could help understand which e-cigarette ingredients make them more appealing or addictive, potentially informing future regulations.
What could go wrong
This is a small, early-stage study (66 participants) measuring subjective responses, not health outcomes. Results may not apply to all users or predict long-term addiction risk.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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JB Pierce Lab
RECRUITINGNew Haven, Connecticut, 06519, United States