Flavor test: do E-Cigarette tastes hook smokers differently by age?
NCT ID NCT03635333
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how flavors in e-cigarettes affect how much adult smokers like and want them. It included 130 smokers aged 21-50 who used only e-cigarettes for two weeks. The goal was to measure their reactions, not to treat or cure any condition.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1
The first testing in people. Mainly checks safety and dose, usually in a small group.
- Participants
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130 people
The number who actually took part.
- Started
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May 2019
- Finished
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Jul 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 to 50 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Ages 21-34 years or 35 -50 years * Able to read and write * Smoking \>/= 1 cigarettes or cigars/day * Willing to abstain from regular smoking for 2 weeks and use only e-cigarettes * Not seeking treatment to stop smoking Exclusion Criteria: * Daily use of other drugs including prescribed psychoactive drugs * Any significant current medical or psychiatric condition * Known hypersensitivity to propylene glycol * Pregnant or lactating females
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CMHC, Substance Abuse Center
New Haven, Connecticut, 06519, United States
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