Blood test could help alaska natives quit smoking for good

NCT ID NCT06556238

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study is testing whether a simple blood test that measures how fast a person breaks down nicotine can help doctors choose the best medication to help Alaska Native and American Indian people quit smoking. The study will enroll 50 adults who smoke daily and are ready to quit. Researchers will see if participants and healthcare providers find this personalized approach acceptable and practical to use in a real clinic setting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Nicotine Metabolite Ratio (NMR) blood test to guide medication choice
What this could lead to
If successful, this could lead to a more personalized and effective way to help Alaska Native people quit smoking by matching them with the right medication based on how fast they break down nicotine.
What could go wrong
This is a very small pilot study with only 50 participants and no comparison group, so results may not be generalizable. The main goal is to see if the approach is acceptable and feasible, not yet to prove it helps people quit.

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Conditions

The condition(s) this trial relates to.

Smoking Cessation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Anchorage Native Primary Care Center

    RECRUITING

    Anchorage, Alaska, 99508, United States

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