Hormone pill may help new mothers quit smoking for good
NCT ID NCT04783857
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether taking progesterone pills can prevent new mothers from relapsing into cigarette smoking after childbirth. Researchers will enroll 171 women who recently quit smoking during pregnancy to see if the hormone helps them stay smoke-free and reduces secondhand smoke exposure for their babies. The trial also looks at differences in outcomes across racial and ethnic groups.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Progesterone 200 mg oral capsule
What this could lead to
If it works, this could offer a hormone-based option to help new mothers avoid smoking relapse, improving their health and reducing infants' exposure to secondhand smoke.
What could go wrong
This is a Phase 4 study with 171 participants, so results may not apply to all women. Progesterone can cause side effects like dizziness or mood changes, and the effect on long-term abstinence is uncertain.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Minnesota
Minneapolis, Minnesota, 55455, United States