Can a phone app help people with HIV kick the smoking habit?

NCT ID NCT06883097

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study compares two smartphone apps designed to help people living with HIV quit smoking. Participants will use one of the apps for about six months and also receive nicotine patches and gum. The goal is to see which app works better at helping people stay smoke-free, using breath and saliva tests to confirm results.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
smartphone app (Learn to Quit-HIV or QuitStart) plus nicotine replacement therapy (patches and gum)
What this could lead to
If successful, this could provide an effective, accessible tool to help people living with HIV quit smoking, reducing their risk of cancer and other diseases.
What could go wrong
This is a mid-stage trial with 314 participants, so results may not apply to everyone. The apps may not be more effective than standard support, and quitting smoking is difficult even with help.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Wake Forest University, Implementation Science

    RECRUITING

    Winston-Salem, North Carolina, 27101, United States

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