Can your genes help you quit smoking? new study tests personalized approach

NCT ID NCT05846841

Recruiting now Disease control Sponsor: Washington University School of Medicine Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 04, 2026 · Updated 2 times

Summary

This study tests whether giving smokers a personalized quit plan based on their genes, health history, and biomarkers helps more people stop smoking than standard advice. About 850 smokers and their doctors from primary care clinics will take part. The goal is to see if tailored recommendations increase medication use and quit rates.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: behavioral intervention (personalized tobacco treatment recommendations based on clinical, genetic, and biomarker information)
What this could lead to: If successful, this approach could make smoking cessation treatments more effective by tailoring them to each person's unique profile.
What could go wrong: This is a relatively early-stage behavioral study, and the personalized approach may not significantly improve quit rates over standard care. Results depend on clinician and patient adherence.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PHYSICIAN'S ROLE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

nicotine dependence Smoking Smoking Cessation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PHYSICIAN'S ROLE SMOKING SMOKING CESSATION

Contacts and locations

Locations

Washington University School of Medicine
RECRUITING

St Louis, Missouri, 63110, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.