Can your genes help you quit smoking? new study tests personalized approach

NCT ID NCT05846841

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving smokers a personalized quit plan based on their genes, health history, and biomarkers helps more people stop smoking than standard advice. About 850 smokers and their doctors from primary care clinics will take part. The goal is to see if tailored recommendations increase medication use and quit rates.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

behavioral intervention (personalized tobacco treatment recommendations based on clinical, genetic, and biomarker information)

What this could lead to

If successful, this approach could make smoking cessation treatments more effective by tailoring them to each person's unique profile.

What could go wrong

This is a relatively early-stage behavioral study, and the personalized approach may not significantly improve quit rates over standard care. Results depend on clinician and patient adherence.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Smoking Smoking Cessation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Washington University School of Medicine

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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    Contact