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Can an AI chatbot help cancer patients kick the habit?

NCT ID NCT07827066

Symptom relief Sponsor: Sun Yat-sen University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 18, 2026 · Last updated Sep 18, 2026

Summary

Researchers are testing whether an AI chatbot on WeChat helps early-stage cancer patients quit smoking. The chatbot uses the Multi-Theory Model to offer personalized advice, emotional support, and habit tracking around the clock. The trial compares the chatbot with phone-based professional counseling and routine health education. Participants are randomly assigned to one of the three groups, and researchers measure quitting rates over six months using breath and saliva tests.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
an AI chatbot that delivers smoking cessation support based on the Multi-Theory Model
What this could lead to
If it works, this could give cancer patients a round-the-clock, low-cost way to get quitting support without waiting for a counselor.
What could go wrong
Chatbots can lose people's attention, and quitting smoking is hard even with human help. The trial is small and only in Chinese-speaking patients, so results may not apply broadly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 156 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age ≥18 years, diagnosed with early-stage cancer (AJCC 8th edition clinical stage cTNM 0-II); 2. Smoked in the past 30 days, with an average daily consumption of \> 1 cigarette, and an exhaled Carbon Monoxide (CO) level ≥ 4 ppm; 3. Able to communicate using WeChat; 4. Able to understand and read Chinese, and possess conversational Mandarin skills; 5. Willing to participate in this study and sign the informed consent form. Exclusion Criteria: 1. Individuals who are unable to communicate due to severe mental or physical illness; 2. Individuals currently participating in other tobacco control research projects; 3. Individuals whose cancer has metastasized.

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Conditions

The condition(s) this trial relates to.

neoplasm Smoking Cessation Tobacco Use Cessation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ai agent Early-stage cancer Smoking cessation

How to take part

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  1. The official record

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  2. A doctor treating you

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