Flavor variety may boost quit rates in smokers switching to E-Cigs

NCT ID NCT07598136

Recruiting now Disease control Sponsor: RAI Services Company Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving smokers a choice of e-cigarette flavors (tobacco, menthol, mint, or other) helps them stop smoking regular cigarettes. About 1,280 adult smokers will use a provided e-cigarette device for 13 weeks, and researchers will check who stays away from cigarettes. The goal is to see if more flavor options lead to higher quit rates.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: electronic nicotine delivery system (ENDS) with various e-liquid flavors
What this could lead to: If successful, this could show that offering a variety of flavors in e-cigarettes helps more smokers switch away from combustible cigarettes.
What could go wrong: This is a behavioral study, not a drug trial, and results may not apply to all smokers. The long-term health effects of ENDS are still uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for SMOKING are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

nicotine dependence Smoking Tobacco Smoking Tobacco Use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SMOKING TOBACCO

Contacts and locations

Locations

L&E Raleigh
RECRUITING

Raleigh, North Carolina, 27612, United States
Sago Atlanta
RECRUITING

Atlanta, Georgia, 30328, United States
Sago Dallas
RECRUITING

Dallas, Texas, 75254, United States
Sago Houston
RECRUITING

Houston, Texas, 77027, United States
Sago Orlando
RECRUITING

Maitland, Florida, 32751, United States
Sago Philadelphia
RECRUITING

Philadelphia, Pennsylvania, 19103, United States
Sago St. Louis
RECRUITING

St Louis, Missouri, 63131, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.