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Smoking ban may shield Non-Smokers' blood vessels

NCT ID NCT02779127

Knowledge-focused Sponsor: University Hospital, Toulouse Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This study looks at whether a ban on smoking in pubs, restaurants, and nightclubs improves blood vessel function in non-smoking workers who were regularly exposed to secondhand smoke. Researchers measure how well the brachial artery expands after a brief blood flow interruption, comparing workers exposed to smoke with those not exposed. The goal is to see if ending passive smoke exposure leads to healthier blood vessels and a lower risk of heart problems.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If it works, this could provide evidence that public smoking bans improve cardiovascular health in non-smokers.
What could go wrong
This is an observational study with a small sample size (49 participants), so results may not apply broadly. Changes in vessel function could be small or temporary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

49 people

The number who actually took part.

Started

Dec 2007

Finished

Jun 2008

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Subject exposed at least one hour per day to passive smoking at work during at 1 year minimum for intervention arm and non exposed to passive smoking for control group. * Subject having signed informed consent * Subject with social security insurance or equivalent Exclusion Criteria: * Exposition to passive smoking at home * Active smokers (at least 1 cigarette per day or having drawn up active smoking for less than a month) * Medical history of homozygote familial hypercholesterolemia * Usage of lipid lowering treatment in the month before the inclusion * Hepatic active pathology or hepatocellular insufficiency * Severe kidney disease (with creatine clearance less than 30 ml per minute) * Evolutive cancer * Usage of concomitant treatment as : insulin, nitro-derivatives and statins * Medical history of alcoholism or drug use last year * Medical history of permanent systolic hypotension (systolic blood pressure less than 90 mmHg) or non controled hypertension (systolic blood pressure higher than 200 mmHg and diastolic blood pressure 110 mmHg) * Active cardiovascular disease * Psychological or medical conditions incompatible with the study according to investigator opinion * Participation to another study with experimental product or subject having received an study treatment within 4 weeks before inclusion * Impossibility to follow the study procedure * Pregnancy and breastfeeding * Subject protected by french law

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Conditions

The condition(s) this trial relates to.

Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Smoking

Contacts and locations

Locations

  • Toulouse, Rangueil Hospital

    Toulouse, 65360, France

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