New nicotine pouches put to the test: are they less addictive than cigarettes?

NCT ID NCT07685795

Not yet recruiting Knowledge-focused Sponsor: RAI Services Company Source: ClinicalTrials.gov ↗

First seen Jul 06, 2026 · Last updated Jul 07, 2026 · Updated 1 time

Summary

This study looks at whether four new oral nicotine products (like pouches) are less appealing and addictive than traditional cigarettes and moist snuff. About 50 healthy adults who smoke and use smokeless tobacco will try each product in a clinic setting. Researchers will measure how much participants like each product, their heart rate, and nicotine levels in the blood.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: nicotine
What this could lead to: If successful, this research could help understand whether these new nicotine products are less addictive than traditional cigarettes or smokeless tobacco.
What could go wrong: This is a small, early-stage study in a controlled clinic setting, so results may not reflect real-world use. The products still contain nicotine, which is addictive.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

nicotine dependence Smoking Tobacco Smoking Tobacco Use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SMOKING SMOKING BEHAVIORS TOBACCO SMOKING TOBACCO USE

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••
Contact

Phone: •••-•••-•••• Email: •••••@•••••

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