Brain zaps for addiction: new study targets relapse with personalized implants

NCT ID NCT06973512

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This pilot study tests a personalized deep brain stimulation (DBS) method for people with severe, treatment-resistant substance use disorders. Ten participants will first undergo detox, then have temporary electrodes placed in their brains to map addiction-related circuits, followed by permanent DBS implantation. The goal is to see if this approach is safe and feasible, with participants followed for one year.

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Conditions

The condition(s) this trial relates to.

Behavior, Addictive substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Centre for Addiction and Mental Health / Toronto Western Hospital

    RECRUITING

    Toronto, Ontario, 399 Bathurst St, Canada

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