ADDICTION

This study tests whether adding regular motivational talks to standard care helps people with alcohol addiction stay sober longer after leaving the hospital. Researchers will compare two groups of 104 adults: one receiving motivational interviews every two weeks for four months, …

This study is testing whether a gentle, non-invasive brain stimulation technique can help people who vape daily reduce their habit. Researchers will give 40 participants either real or fake stimulation sessions for two weeks to see if it lowers the number of times they vape and t…

This study is testing whether combining a gentle, non-invasive brain stimulation technique with specific mental exercises can help people with alcohol use disorder stay sober. Researchers want to see if this 'brain training' improves thinking skills and reduces the chance of rela…

This study is testing whether people with moderate to severe methamphetamine addiction can safely take a high-dose stimulant medication for 25 weeks alongside standard treatment. Researchers want to see if participants stay in the program, take their medication regularly, and are…

This study is testing if semaglutide, a medication currently used for weight loss and diabetes, can help people with alcohol use disorder drink less. About 52 adults will receive weekly injections of either the real medication or a placebo (dummy shot) for 20 weeks. Researchers w…

This study is testing whether a shorter, 12-week therapy program is practical and acceptable for people dealing with both addiction and trauma (PTSD). The program, called ECCCLORE, teaches skills to manage emotions, tolerate distress, and improve relationships. Researchers will e…

This study is testing if adding a high-dose stimulant medication and a reward-based program to standard addiction treatment helps adults with methamphetamine use disorder reduce their drug use. Researchers will compare four different combinations of these approaches over 15 weeks…

This study aims to see if training people who inject drugs to become peer educators for their social networks can help increase HIV testing and the use of prevention services. The research will involve 360 participants from syringe service programs in Maryland. It will compare a …

This study aims to see if brain scans can predict how well teens respond to a cannabis treatment program. Researchers will scan the brains of 80 teens (ages 14-17) who use cannabis, then have them join 10 weeks of virtual sessions where they report use and take drug tests. Teens …

This study aims to develop and test simple computer tasks that can be used during brain scans to better understand how alcohol use disorders affect behavior, thinking, and decision-making. Researchers are recruiting 400 adults, including both healthy volunteers and people with al…

This study aims to understand how people with substance or behavioral addictions progress through the healthcare system over time. Researchers will follow 10,000 participants receiving addiction treatment, tracking their medical, psychological, and social characteristics. The stu…