New combo therapy shows promise in reducing meth use

NCT ID NCT05854667

First seen Jan 04, 2026 · Last updated Apr 25, 2026 · Updated 22 times

Summary

This study tests whether adding a high-dose stimulant medication and/or a reward-based program (contingency management) to standard care helps adults reduce how often they use methamphetamine. About 440 participants aged 18-55 with moderate to severe methamphetamine use disorder will be randomly assigned to one of four groups for 15 weeks. The goal is to see which combination works best to cut down on days of use.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Center for Addiction and Mental Health

    RECRUITING

    Toronto, Ontario, M6J 1HN, Canada

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rapid Access Addiction Medicine Clinic, St. Paul's Hospital

    RECRUITING

    Vancouver, British Columbia, Canada

    Contact

    Contact Email: •••••@•••••

  • River Stone Recovery Centre

    SUSPENDED

    Fredericton, New Brunswick, E3B 1E3, Canada

  • University of Montreal Hospital Research Center

    RECRUITING

    Montreal, Quebec, H2X 0A9, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.