New combo therapy aims to curb meth use in canadian trial

NCT ID NCT05854667

Recruiting now Disease control Sponsor: Centre hospitalier de l'Université de Montréal (CHUM) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a high-dose stimulant medication and/or a reward-based program (contingency management) to standard care helps people reduce how often they use methamphetamine. About 440 adults with moderate to severe methamphetamine use disorder will be randomly assigned to one of four groups for 15 weeks. The goal is to find a more effective way to manage addiction and support recovery.

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Conditions

The condition(s) this trial relates to.

amphetamine abuse Behavior, Addictive methamphetamine dependence substance abuse substance dependence substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ADDICTION ADDICTION, SUBSTANCE METHAMPHETAMINE ABUSE METHAMPHETAMINE-DEPENDENCE

Contacts and locations

Locations

Center for Addiction and Mental Health
RECRUITING

Toronto, Ontario, M6J 1HN, Canada
Rapid Access Addiction Medicine Clinic, St. Paul's Hospital
RECRUITING

Vancouver, British Columbia, Canada
River Stone Recovery Centre
SUSPENDED

Fredericton, New Brunswick, E3B 1E3, Canada
University of Montreal Hospital Research Center
RECRUITING

Montreal, Quebec, H2X 0A9, Canada

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