ADDICTION

This early-phase study looked at whether adding a drug called AUVELITY (a mix of dextromethorphan and bupropion) to standard treatment with buprenorphine/naloxone is safe and might help reduce cravings, withdrawal, and negative feelings in people with opioid use disorder. 18 adul…

This study tested a breathing technique called Holotropic Breathwork to help people recover from addiction. 25 adults in residential treatment or living in the community took part. The goal was to see if the practice is safe, acceptable, and might reduce substance use and improve…

This study tested a 5-day breathwork and meditation program called SKY Recovery in 100 people recovering from substance use disorder at a residential center. Participants were split into two groups: one did the program right away, the other waited. Researchers measured emotional …

This study tested whether giving a single dose of pregabalin (a nerve pain medication) about an hour before kidney stone surgery could reduce pain and the need for opioid painkillers afterward. 118 adults having ureteroscopy with a ureteral stent were randomly assigned to receive…

This pilot study tested whether low-frequency repetitive transcranial magnetic stimulation (rTMS) to a specific brain area could reduce cravings in heavy smokers who had failed multiple quit attempts. 39 highly nicotine-dependent adults received rTMS alongside nicotine replacemen…

This early-stage study tested whether cannabidiol (CBD) is safe and helpful for people who are being treated for opioid addiction and also have long-term pain. Seven adults on methadone or buprenorphine received CBD or a placebo in a controlled setting. Researchers measured sedat…

This pilot study tested whether adding protein supplements to the diet could lower cravings in people hospitalized for addiction. 28 adults spent one week with protein supplements and one week without, rating their cravings daily. The goal was to see if protein could help ease th…

This study tested whether N-acetylcysteine (NAC), a supplement, can help people who struggle with both alcohol use disorder and PTSD. 182 adults took NAC or a placebo to see if it reduced drinking and PTSD symptoms. The goal was to find a safer, more accessible treatment option f…

This study used artificial intelligence to analyze personality and behavior questionnaires from 155 adults in residential treatment for substance use disorder. The goal was to find hidden subgroups of patients that might need different treatment approaches. No treatment was given…

This study tested a training program called First Face, designed to help community members recognize and respond to mental health crises. About 92 staff from the Healing Lodge of the Seven Nations took surveys before, right after, and 3 months after training. The goal was to see …

This study looked at how to best prevent tuberculosis (TB) in Malaysian prisoners, especially those with opioid addiction and HIV. Researchers compared a standard 9-month daily TB prevention medicine to a shorter 3-month weekly option. The goal was to see which approach works bet…

This study screened nearly 7,000 adults to find people who might be eligible for future research on drug addiction, treatments, and brain effects. Participants had phone and in-person interviews, medical exams, and lab tests. No treatment was given—this was only to build a pool o…