Could a single pill before kidney stone surgery cut opioid use?

NCT ID NCT04122196

First seen Nov 12, 2025 · Last updated May 16, 2026 · Updated 25 times

Summary

This study tested whether giving a single dose of pregabalin (a nerve pain medication) about an hour before kidney stone surgery could reduce pain and the need for opioid painkillers afterward. 118 adults having ureteroscopy with a ureteral stent were randomly assigned to receive either pregabalin or a placebo. Researchers then measured pain scores and how much opioid medication patients used after surgery.

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Contacts and locations

Locations

  • University of Missouri-Columbia

    Columbia, Missouri, 65212, United States

Conditions

Explore the condition pages connected to this study.