Could a cough medicine help fight opioid addiction?

NCT ID NCT05976646

First seen May 08, 2026 ยท Last updated May 08, 2026

Summary

This study tested whether adding a drug called AUVELITY (dextromethorphan and bupropion) to standard buprenorphine/naloxone treatment is safe and helpful for people with opioid use disorder. 18 adults on stable buprenorphine treatment took part. Researchers measured safety (heart rate, blood pressure, side effects) and early signs of benefit like reduced cravings and withdrawal. The goal is to find better ways to manage opioid addiction.

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Contacts and locations

Locations

  • CARI Research Clinic- VCU Institute for Drug and Alcohol Studies

    Richmond, Virginia, 23219, United States

Conditions

Explore the condition pages connected to this study.