Brain scans reveal Nicotine's hidden impact on depression
NCT ID NCT05538910
First seen Jan 16, 2026 · Last updated May 16, 2026 · Updated 15 times
Summary
This study looks at how nicotine changes brain activity in people with major depressive disorder (MDD) compared to those without. Researchers will use MRI scans to measure brain function after giving participants either nicotine or a placebo. The goal is to understand why people with depression are more likely to use nicotine and have a harder time quitting.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institute on Drug Abuse
RECRUITINGBaltimore, Maryland, 21224, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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