SUBSTANCE USE DISORDER

This study tests a program called Fathers for Change (F4C) for 280 fathers who struggle with substance misuse and have been violent toward family. The program aims to help them control emotions, stop substance use, and prevent violence. Researchers compare F4C to standard drug co…

This study tests a new behavioral program called InTEGRA for teens aged 14-21 with alcohol or cannabis use disorder. It combines 12-step facilitation with motivational and cognitive-behavioral therapy. Researchers will compare it to standard therapy to see if it leads to more day…

This study looks at whether treating obstructive sleep apnea (OSA) early with a positive airway pressure (PAP) device can improve outcomes for veterans with both PTSD and substance use disorder. About 194 veterans in a residential treatment program will either receive PAP therapy…

This study tests a therapy called Mothering from the Inside Out (MIO) for mothers recovering from substance use disorders. The goal is to help them build stronger relationships with their young children and reduce parenting stress. Researchers will enroll 200 mothers from outpati…

This study tests a digital app called Enhearten designed to reduce self-stigma in pregnant and postpartum women with substance use disorder. The app provides just-in-time support to help women feel less judged and stay on track with addiction treatment. Researchers will compare t…

This study tests a program called Contingency Management that gives Veterans rewards for quitting smoking, verified by breath tests. Researchers will first gather feedback from Veterans and staff, then run a small pilot with 20 Veterans over 5 weeks. If successful, a larger trial…

This study looks at how nicotine changes brain function in people with and without major depressive disorder (MDD). Researchers will give 620 non-smokers either a nicotine patch or a placebo and then scan their brains using MRI. Participants will also answer questions about their…

This study screens up to 10,000 adults aged 18-99 who have current, past, or no substance or alcohol use disorders. Participants undergo one visit with tests like physical exams, blood work, memory tests, and mental health evaluations. The goal is to find eligible volunteers for …

This study is collecting information from 80 adults who have both ADHD and an addiction. Researchers will track their symptoms and daily functioning over 12 months to better understand how these conditions affect each other. The goal is to gather data that could improve future tr…

This study aims to understand what causes substance use and cravings in veterans, especially when combined with issues like anxiety, depression, or PTSD. Researchers will create a personal model for each participant showing their unique triggers, then give them feedback on how to…

This study is looking at 120 people who are already in treatment for abusing opioids and/or benzodiazepines (anti-anxiety drugs). Researchers want to understand why people use these drugs together, which greatly raises the risk of overdose and death. Participants will complete in…

This study is testing a cooking and nutrition program for 50 people in Texas who are recovering from opioid use and living in recovery homes while on medication therapy. The program aims to improve their eating habits and confidence in cooking skills. Participants will fill out q…

This study is creating a program called START-VET to help veterans with mental illness or substance use disorders who have recently left prison. Researchers will work with 20 veterans to develop transition materials and tools. The goal is to improve quality of life and reduce cri…