SUBSTANCE USE DISORDER
Clinical trials for SUBSTANCE USE DISORDER explained in plain language.
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New therapy aims to help recovering moms and their kids thrive
Disease control Recruiting nowThis study is testing a special parenting therapy called Mothering from the Inside Out (MIO) for mothers who are in treatment for substance use. The goal is to see if adding this therapy to their usual treatment helps improve their parenting skills, reduces stress, and supports t…
Matched conditions: SUBSTANCE USE DISORDER
Phase: NA • Sponsor: Baystate Medical Center • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New hope for veterans: treating sleep apnea to boost PTSD and addiction recovery
Disease control Recruiting nowThis study examines whether treating obstructive sleep apnea (using a positive airway pressure device) during a 28-day residential treatment program improves outcomes for Veterans with both PTSD and substance use disorder. Researchers will compare immediate treatment to a delayed…
Matched conditions: SUBSTANCE USE DISORDER
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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VA offers cash rewards to veterans trying to quit smoking
Disease control Recruiting nowThis study is testing a mobile phone program that gives Veterans small rewards for quitting smoking, especially those getting lung cancer screening or cancer care. First, researchers will design the program with feedback from Veterans and staff. Then, they'll test if the reward p…
Matched conditions: SUBSTANCE USE DISORDER
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Mar 24, 2026 12:03 UTC
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VA study maps Veterans' personal triggers to fight addiction
Disease control Recruiting nowThis study aims to help Veterans with substance use disorders by creating personalized models that show what triggers their substance use and related mental health symptoms like anxiety and depression. Researchers will track 74 Veterans' daily experiences using smartphone surveys…
Matched conditions: SUBSTANCE USE DISORDER
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Mar 23, 2026 15:29 UTC
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New program aims to help veterans successfully return from prison
Disease control Recruiting nowThis study is creating a support program and assessment tools to help veterans with mental health or substance use issues transition from prison back to community life. Researchers will first interview recently released veterans about their experiences, then develop materials bas…
Matched conditions: SUBSTANCE USE DISORDER
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Mar 23, 2026 15:16 UTC
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New app aims to lift the burden of shame for moms battling addiction
Symptom relief Recruiting nowThis study is testing a smartphone app called Enhearten, designed to help pregnant women and new mothers who have a substance use disorder. The app aims to reduce feelings of shame and stigma, and to support them in sticking with their treatment plans. Researchers will compare ou…
Matched conditions: SUBSTANCE USE DISORDER
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Apr 01, 2026 14:42 UTC
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Brain scans reveal why depression may fuel nicotine risk
Knowledge-focused Recruiting nowThis study aims to understand why people with major depression are twice as likely to use nicotine and have a harder time quitting. Researchers will use brain scans (MRI) to see how a single dose of nicotine affects brain function in non-smokers with and without depression. The g…
Matched conditions: SUBSTANCE USE DISORDER
Phase: NA • Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Massive 10,000-Person study aims to unlock the mysteries of addiction
Knowledge-focused Recruiting nowThis study is a large screening program to find people for future research on addiction. It aims to understand why some people use drugs, why some get addicted, and why others never use them. Researchers will screen up to 10,000 adults, with and without substance use disorders, u…
Matched conditions: SUBSTANCE USE DISORDER
Sponsor: National Institute on Drug Abuse (NIDA) • Aim: Knowledge-focused
Last updated Mar 10, 2026 12:53 UTC