SUBSTANCE USE DISORDER

This trial tests whether adding substance use disorder resources to existing behavioral health services in pediatric primary care clinics can improve care for adolescents with opioid use disorder. The approach includes training, stigma reduction, and brief interventions during re…

This trial tests a 12-session cognitive-behavioral therapy designed to help people with substance use who also struggle with anxiety or depression. The therapy focuses on improving emotion regulation—the ability to understand and manage emotions—which may reduce addictive behavio…

This study looks at whether adding a structured therapy journal to standard cognitive behavioral therapy (CBT) helps people with mental health conditions like depression, anxiety, or eating disorders feel better faster. About 80 adults in outpatient therapy will be randomly assig…

This study tests whether a coaching program called COSTARS helps child welfare supervisors better support their teams, including caseworkers and peer mentors with lived recovery experience. About 200 supervisors in Ohio's START program will either receive coaching or continue usu…

This early study is testing whether focused ultrasound, a non-invasive technique that uses sound waves to target specific brain areas, is safe and feasible for people with opioid or other substance use disorders. The study involves 20 adults aged 22-60 who are currently in treatm…

This study tests whether methylphenidate (Ritalin) can help weaken memories that link drug cues to cocaine use. Fifty-one adults with cocaine use disorder will receive either methylphenidate or a placebo before recalling drug-related memories, while brain activity and skin respon…