New study aims to uncover why opioid and Anti-Anxiety drug mix is so deadly

NCT ID NCT03696017

Recruiting now Knowledge-focused Sponsor: Wayne State University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is looking at 120 people who are already in treatment for abusing opioids and/or benzodiazepines (anti-anxiety drugs). Researchers want to understand why people use these drugs together, which greatly raises the risk of overdose and death. Participants will complete interviews, questionnaires, and computer tasks to measure mood, thinking, pain, sleep, and drug use patterns. The goal is to find better ways to prevent and treat this dangerous combination.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could identify key traits that make people more likely to misuse opioids and benzodiazepines together, pointing toward better prevention and treatment strategies.
What could go wrong: This is an observational study with no treatment being tested. It will not directly change patient care, and results may not apply to all populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

opiate dependence polysubstance abuse, susceptibility to substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POLYSUBSTANCE ABUSE

Contacts and locations

Locations

Tolan Park Medical Building
RECRUITING

Detroit, Michigan, 48201, United States

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