Can your nose predict brain health? new study tests smell and choices in HIV and addiction

NCT ID NCT07637669

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This study looks at how HIV and substance use disorder (SUD) affect the sense of smell and decision-making. Researchers will test 120 adults aged 18–65, including people with HIV, SUD, both, or neither. Participants will complete smell tests and computer tasks over two visits, and some may have a brain scan. The goal is to understand how these conditions impact brain function, not to provide treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could reveal how HIV and substance use affect the brain, potentially pointing to new ways to detect or treat thinking problems.

What could go wrong

This is an observational study, not a treatment trial. It will not directly improve health, and results may not apply to everyone with HIV or substance use disorder.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Anosmia HIV infectious disease substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institute on Drug Abuse

    Baltimore, Maryland, 21224, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••