New therapy aims to boost teen recovery from substance use

NCT ID NCT06395467

Recruiting now Disease control Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a new behavioral program called InTEGRA for teens aged 14-21 with alcohol or cannabis use disorder. It combines 12-step facilitation with motivational and cognitive-behavioral therapy. Researchers will compare it to standard therapy to see if it leads to more days without substance use and fewer negative consequences.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: behavioral therapy (InTEGRA)
What this could lead to: If it works, this could offer a more effective way to help teens reduce substance use and stay in recovery.
What could go wrong: This is a Phase 2 trial, so results are still early. The therapy may not work better than existing treatments, and individual outcomes vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

alcohol abuse cannabis dependence substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALCOHOL USE DISORDER CANNABIS USE DISORDER

Contacts and locations

Locations

MGH Department of Psychiatry
RECRUITING

Boston, Massachusetts, 02114, United States
UConn Health
RECRUITING

Farmington, Connecticut, 06032, United States

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