Can a structured care pathway ease teen depression?

NCT ID NCT05142683

Recruiting now Disease control Sponsor: Centre for Addiction and Mental Health Source: ClinicalTrials.gov ↗

First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time

Summary

This trial is testing whether an integrated care pathway (ICP) can help reduce depressive symptoms in adolescents aged 13 to 18 who seek help at community mental health agencies. Participants will receive either the ICP or treatment as usual, and researchers will track changes in mood, daily functioning, and caregiver-reported behaviors over 24 weeks. The goal is to see if a more coordinated, multi-component approach leads to better outcomes than standard care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Integrated Care Pathway (CARIBOU-2) - a coordinated, multi-component care approach for adolescent depression
What this could lead to: If effective, this care pathway could offer a structured, evidence-based approach to treating adolescent depression in community settings, potentially improving outcomes for many teens.
What could go wrong: This is a quasi-experimental study, not a randomized trial, so results may be influenced by site differences. The intervention's success depends on how well it is implemented across various community agencies.

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Conditions

The condition(s) this trial relates to.

Depression major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MAJOR DEPRESSIVE DISORDER

Contacts and locations

Locations

Centre for Addiction and Mental Health
RECRUITING

Toronto, Ontario, Canada

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