Scientists use advanced MRI to map addiction in the brain

NCT ID NCT01036581

Recruiting now Knowledge-focused Sponsor: National Institute on Drug Abuse (NIDA) Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 05, 2026 · Updated 12 times

Summary

This study is developing new MRI techniques to better understand how drug addiction changes the brain. Researchers will scan 1,000 healthy adults, smokers, and drug users to improve imaging methods. The goal is to create tools that can reveal the brain's structure and function in addiction, which may lead to better treatments in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Magnetic stimulation devices (TMS and TRPMS)
What this could lead to: If successful, this could lead to better brain imaging tools to study addiction and develop more effective treatments.
What could go wrong: This is an early-stage, observational study focused on developing techniques, not testing a treatment. It may not directly lead to new therapies.

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Conditions

The condition(s) this trial relates to.

nicotine dependence substance abuse substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DRUG ABUSE NICOTINE DEPENDENCE

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

National Institute on Drug Abuse, Biomedical Research Center (BRC)
RECRUITING

Baltimore, Maryland, 21224, United States

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