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Yale study tests sleep fix to kick smoking habit

NCT ID NCT06609369

Recruiting now Disease control Sponsor: Yale University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a behavioral sleep intervention combined with the drug varenicline can help heavy smokers quit. Researchers will measure sleep quality, smoking habits, and brain activity in 114 participants. The goal is to see if improving sleep reduces negative emotions and boosts self-control, making it easier to stay smoke-free.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Varenicline
What this could lead to
If successful, this could point toward a more effective smoking cessation approach that addresses sleep problems.
What could go wrong
This is a small Phase 2 trial, so results may not apply to all smokers. The intervention is complex and may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

insomnia nicotine dependence Tobacco Use Tobacco Use Cessation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INSOMNIA TOBACCO CESSATION TOBACCO USE

Contacts and locations

Locations

  • Connecticut Mental Health Center

    RECRUITING

    New Haven, Connecticut, 06519, United States

    Contact Email: •••••@•••••

  • Yale University

    RECRUITING

    New Haven, Connecticut, 06520, United States

    Contact Email: •••••@•••••

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