Vapes vs. patches: new study tests if E-Cigarettes help smokers in recovery kick the habit

NCT ID NCT06922617

Recruiting now Disease control Sponsor: Medical University of South Carolina Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether e-cigarettes (nicotine vapes) can help people who are in treatment for substance use disorder quit smoking. Participants will either switch to e-cigarettes or use FDA-approved nicotine patches and lozenges, with weekly counseling. The goal is to see which approach works better for staying smoke-free.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: e-cigarettes (nicotine vapes) and nicotine replacement therapy (patches and lozenges)
What this could lead to: If it works, this could offer a practical way for people in addiction treatment to quit smoking, potentially improving their overall health.
What could go wrong: This is a relatively small, early-stage study (240 people) and results may not apply to everyone. E-cigarettes have their own health risks and may not help everyone quit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

nicotine dependence substance-related disorder Tobacco Use

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SUBSTANCE USE DISORDERS TOBACCO USE

Contacts and locations

Locations

Behavioral Health Services of Pickens County
RECRUITING

Pickens, South Carolina, 29671, United States
MUSC Charleston, Center for Drug and Alcohol Problems
RECRUITING

Charleston, South Carolina, 29425, United States
Phoenix Center
RECRUITING

Greenville, South Carolina, 29607, United States
Shoreline Behavioral Health Services
RECRUITING

Conway, South Carolina, 29526, United States

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