Could a nicotine patch replace opioids for Post-Surgery pain in smokers?
NCT ID NCT07250230
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study is testing whether a high-dose nicotine patch can reduce pain and the need for opioid painkillers in male smokers who are having chest surgery. The patch is given before and after surgery. The study will track how much pain medication participants use. It includes 80 male smokers aged 18-75 who are undergoing lung surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
nicotine patch
What this could lead to
If it works, this could point toward a non-opioid way to manage pain after surgery for smokers, potentially reducing opioid side effects.
What could go wrong
This is a small pilot study with only 80 men, so results may not apply to everyone. Nicotine patches can cause side effects like skin irritation, dizziness, or nausea.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Department of Anaesthesiology and Perioperative Medicine, People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, Zhengzhou, Henan
RECRUITINGZhengzhou, Henan, 450003, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••