CBD put to the test: could it curb cravings and calm nerves in smokers?
NCT ID NCT07001930
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This early-stage study at Johns Hopkins is testing whether cannabidiol (CBD) can reduce stress and nicotine withdrawal symptoms in people who smoke. Ninety healthy smokers will receive CBD and then be exposed to stress while researchers measure their mood, heart rate, and stress hormones. The goal is to see if CBD can make quitting easier by easing the unpleasant effects of withdrawal.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Epidiolex (cannabidiol, CBD)
What this could lead to
If it works, this could point toward a way to use CBD to help people quit smoking by reducing stress and withdrawal symptoms.
What could go wrong
This is an early Phase 1 study with only 90 people, so results may not apply broadly. CBD may not reduce stress or withdrawal better than a placebo.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Behavioral Pharmacology Research Unit
RECRUITINGBaltimore, Maryland, 21224, United States