Ancient herb meets modern science: could ashwagandha ease PCOS symptoms?
NCT ID NCT07750899
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This trial tests whether a standardized ashwagandha (Withania somnifera) extract, combined with vitamin D and folate, can improve depression, stress, sleep, and metabolic health in women with polycystic ovary syndrome (PCOS). Participants will take either the ashwagandha blend or a comparator supplement daily for a period. Researchers will measure changes in mood questionnaires, stress levels, blood pressure, body composition, and blood markers to see if the herb offers added benefits.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Withania somnifera (ashwagandha) extract combined with vitamin D and folate
- What this could lead to
- If it works, this could offer a safe, easy-to-use supplement to complement standard PCOS care, potentially improving mood, stress, and metabolic health.
- What could go wrong
- This is a small early-stage trial, so results may not apply broadly. The supplement may not outperform the active comparator, and individual responses can vary.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Medical University of Lodz
Lodz, Poland
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